A Two-Stage Deep Learning Framework for Skin Lesion Detection and Classification Using ResNet18 and EfficientNet-B4
Abstract
Skin diseases encompass a wide range of conditions that require an early and accurate diagnosis for effective treatment. This paper presents a two-stage deep learning framework for automated skin lesion detection and classification using deep convolutional neural networks. The first stage uses a ResNet18 model to detect the presence of a lesion in dermoscopic images. If a lesion is detected, the image is transferred to an EfficientNetB4 model for multiclass classification. Our approach integrates data augmentation, hair removal preprocessing, learning rate scheduling, and early stopping to enhance model performance and robustness. The framework is trained and evaluated on the HAM10000 dataset, addressing challenges such as class imbalance, model fine-tuning, and overfitting. Experimental results demonstrate the effectiveness of this method in accurately identifying and categorizing skin lesions, contributing to the advancement of deep learning-based dermatological diagnosis.
Keywords:
Deep Learning, Convolutional Neural Network, Skin Lesion Detection, Skin Lesion Classification, image preprocessing, ResNet18, EfficientNet-B4, data enhancement, HAM10000 data set, Dermatology, Computer-aided diagnosis, Medical image analysisPublished
Issue
Section
License
Copyright (c) 2025 International Journal on Emerging Research Areas

This work is licensed under a Creative Commons Attribution 4.0 International License.
All published work in this journal is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
How to Cite
Similar Articles
- Minu Cherian, Elzabeth Bobus, Bala Susan Jacob, M Annapoorna, Ashwin Mathew Zacheria, Empowering Laptop Selection with Natural Language Processing Chatbot and Data Driven Filtering Assistance , International Journal on Emerging Research Areas: Vol. 4 No. 1 (2024): IJERA
- Lis Jose, Albin John Wilson, Akshay Sebastian, Alisha Ann Subash, Agnes James, SafeRoute-A Comprehensive Travel Solution , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- Nrupan Murali, Nebin Siby Sam, Syam Gopi, Pranav Parappukaran Itteera, Rahul M, School Grid:Smart School Ranking and Management System , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- Aditya Ajay, Akhil S Nambiar, Midhun P Mathew, Adon Jobi, Aiswarya Manoj, Emergency Patient Record Transfer System , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- P S Aswin, Archana Madhusudhanan , Athulya Sajeev, Neeha Moideen , C R Suhail, Revolutionizing Football Management: A Data-Driven Approach with Random Forest Regressor , International Journal on Emerging Research Areas: Vol. 4 No. 1 (2024): IJERA
- Nandana L P, Nanda Santhosh, Nupa Babu, Neha Biju, Shiney Thomas, Alumni Connect: A Conceptual Approach of Alumni Network Management with Integrated Web-based System , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- S Adithyakrishnan, U Anjukrishna, Rohith Manuel Philip, P Careena, A Comprehensive Review on Diagnosis and Classification of Various Respiratory Diseases , International Journal on Emerging Research Areas: Vol. 3 No. 1 (2023): IJERA
- Arya Raj S, R Gopika Krishnan, Drishya Das, Rohith R, Jocelyn Ann Joseph, Personality Profiling Using CV Analysis , International Journal on Emerging Research Areas: Vol. 4 No. 1 (2024): IJERA
- Manju Susan Thomas, Juby Mathew, The Integration of Trustworthy AI Values: A Comprehensive Model for Governance, Risk, and Compliance in Audit Architecture Framework context , International Journal on Emerging Research Areas: Vol. 3 No. 2 (2023): IJERA
- Adhil Salim, Advaith Manoj, Alan Thomas Shaji, The Future of Encryption in the Face of Advancing Quantum Computing Technology , International Journal on Emerging Research Areas: Vol. 3 No. 1 (2023): IJERA
You may also start an advanced similarity search for this article.
