A Two-Stage Deep Learning Framework for Skin Lesion Detection and Classification Using ResNet18 and EfficientNet-B4
Abstract
Skin diseases encompass a wide range of conditions that require an early and accurate diagnosis for effective treatment. This paper presents a two-stage deep learning framework for automated skin lesion detection and classification using deep convolutional neural networks. The first stage uses a ResNet18 model to detect the presence of a lesion in dermoscopic images. If a lesion is detected, the image is transferred to an EfficientNetB4 model for multiclass classification. Our approach integrates data augmentation, hair removal preprocessing, learning rate scheduling, and early stopping to enhance model performance and robustness. The framework is trained and evaluated on the HAM10000 dataset, addressing challenges such as class imbalance, model fine-tuning, and overfitting. Experimental results demonstrate the effectiveness of this method in accurately identifying and categorizing skin lesions, contributing to the advancement of deep learning-based dermatological diagnosis.
Keywords:
Deep Learning, Convolutional Neural Network, Skin Lesion Detection, Skin Lesion Classification, image preprocessing, ResNet18, EfficientNet-B4, data enhancement, HAM10000 data set, Dermatology, Computer-aided diagnosis, Medical image analysisPublished
Issue
Section
License
Copyright (c) 2025 International Journal on Emerging Research Areas

This work is licensed under a Creative Commons Attribution 4.0 International License.
All published work in this journal is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
How to Cite
Similar Articles
- Anna N Kurian, Aravind R Nair, Athira Pradeep, Ben V Sajeesh, Traffic Violation Detection Using Machine Learning: A Comprehensive Study , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- Khalid Hareef, Neenu, M N Sulthana , Nesmi Siddique, Number Plate Detection in Fog and Haze , International Journal on Emerging Research Areas: Vol. 3 No. 1 (2023): IJERA
- Adams Mathew, Adithya Sanil, Akhil J Medackal, Nikhil J Medackal, Dyni Thomas, A Literature Review on IMAGE FORGERY DETECTION , International Journal on Emerging Research Areas: Vol. 3 No. 1 (2023): IJERA
- Maria Sajeeve, Karthik Vinod, Kausalya Sumesh, Joby Jose, Minu Cherian, KALO:AI-Powered Precision in Nutrition Tracking , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- Linsa Mathew, Brain Tumor Detection , International Journal on Emerging Research Areas: Vol. 3 No. 1 (2023): IJERA
- George P Kurias, Gokul Krishna AU, Jifith Joseph, Sharunmon R, Linsa Mathew, A Review of Methodologies for Detecting Missing and Wanted People Using Machine Learning and Video Surveillance , International Journal on Emerging Research Areas: Vol. 4 No. 2 (2024): IJERA
- Jyothis Joseph , Ajay K Baiju, Ganga Binukumar, Akshara Manoj, Sandra Elizabeth Rony, A Crowd Monitoring and Real-Time Tracking System using CNN , International Journal on Emerging Research Areas: Vol. 4 No. 1 (2024): IJERA
- Yamini C.K, Ajin krishna K U, Akhil Thilak, Amith Raj P R, Aromal A S, Alex joy, Jishnu Babu T, Jeswin jaison, VIDEO MOMENT RETRIEVAL SYSTEM , International Journal on Emerging Research Areas: Vol. 5 No. 1 (2025): IJERA
- Prayag Suresh, Sneha Susan Alex, Rojan Varghese, Thomas Zacharias, Shiney Thomas, Survey of Strabismus Detection Techniques , International Journal on Emerging Research Areas: Vol. 4 No. 1 (2024): IJERA
- Albin Thomas Lalu, Resmara S, Alen A Thankachen, Sneha Priya Sebastian, Dany Jennez , Lirin Blesson, Kesia Sunny, Fault Detection of Transmission Lines Using Unmanned Aerial Vehicle (UAV) , International Journal on Emerging Research Areas: Vol. 3 No. 1 (2023): IJERA
You may also start an advanced similarity search for this article.
